Chronic health conditions can erode the psychological well-being of adults. At the same time, volunteering can enhance the psychological well-being of adults. The present study examined whether the psychological well-being of adults with chronic health conditions is protected by doing volunteer work for an organization. In addition, we investigated whether the beneficial impact of volunteering on the psychological well-being of adults with chronic health conditions is the same across age, gender, and ethnicity. We carried out a secondary data analysis on 3,673 adults who completed the Arizona health survey (Ahs).